Multiparametric Analysis of Sniff Nasal Inspiratory Pressure Test in Middle Stage Amyotrophic Lateral Sclerosis
نویسندگان
چکیده
منابع مشابه
Maximal values of sniff nasal inspiratory pressure in healthy subjects.
BACKGROUND Inspiratory muscle strength is often better reflected by oesophageal pressure during a maximal sniff (sniff POES) than by maximal inspiratory pressure (PImax). Sniff POES can be estimated non-invasively by measuring the sniff nasal inspiratory pressure (SNIP). The aim was to establish maximal normal values for the SNIP and to compare them with PImax. METHODS One hundred and sixty h...
متن کاملLimitations of sniff nasal pressure as an outcome measurement in amyotrophic lateral sclerosis patients in a clinical trial.
BACKGROUND The forced vital capacity (FVC) is an established measure in amyotrophic lateral sclerosis (ALS) clinical trials. Recently the sniff nasal inspiratory pressure (SNIP) test has been increasingly used as a respiratory measure. OBJECTIVES It was the aim of this study to assess the feasibility of SNIP as an outcome measure in a phase III clinical trial with a lead-in design. METHODS ...
متن کاملReproducibility of twitch mouth pressure, sniff nasal inspiratory pressure, and maximal inspiratory pressure.
Twitch mouth pressure (Pmo,tw) during magnetic phrenic nerve stimulation and sniff nasal inspiratory pressure (SNIP) were recently proposed as alternative noninvasive methods for assessing inspiratory muscle strength. This study aimed to compare their reproducibility with maximal inspiratory pressure (MIP) in normal subjects. Ten healthy subjects were studied at functional residual capacity in ...
متن کاملSniff Nasal Inspiratory Pressure Does Not Decrease in Elderly Subjects
[Purpose] Measurements of inspiratory strength are critical for detecting inspiratory muscle weakness. Sniff nasal inspiratory pressure (SNIP) is a quick, noninvasive measurement of global inspiratory strength; however, it is not clear how many trials are needed for reliable measurements. [Subjects and Methods] One hundred and nineteen subjects (age 39.9±16.5, range 18-69 yrs) completed the stu...
متن کاملInspiratory muscle relaxation rate assessed from sniff nasal pressure.
BACKGROUND Slowing of the maximum relaxation rate (MRR) of inspiratory muscles measured from oesophageal pressure (POES) during sniffs has been used as an index of the onset and recovery of respiratory muscle fatigue. The purpose of this study was to measure MRR at the nose (PNASAL MRR), to investigate its relationship with POES MRR, and to establish whether PNASAL MRR slows with respiratory lo...
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ژورنال
عنوان ژورنال: Frontiers in Neurology
سال: 2018
ISSN: 1664-2295
DOI: 10.3389/fneur.2018.00306